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Nah, *guys*, setelah kita bahas perannya yang super penting di siklus Krebs, sekarang mari kita lihat sisi lain dari **Isositrat Dehidrogenase** yang tak kalah menarik: perannya di luar produksi energi utama. Ingat dua isoform lain yang kita bahas tadi? Yaitu **IDH1** (yang ada di sitoplasma) dan **IDH2** (yang juga di mitokondria, tapi *NADP+-dependent*). Kedua isoform *Isositrat Dehidrogenase* ini memang tidak terlibat langsung dalam produksi NADH untuk rantai transpor elektron, tapi mereka adalah **pahlawan tak terlihat** dalam menjaga kesehatan dan keseimbangan sel kita, terutama dalam hal *manajemen stres oksidatif* dan *biosintesis*. Ini menunjukkan betapa *multifungsi* dan *esensialnya* keluarga enzim ini bagi sel.
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